Role of phospholipid transfer protein in high density lipoprotein mediated reverse cholesterol transport such as lecithin cholesterol acyltransferase lcat cholesteryl ester transfer protein cetp pltps role in reverse cholesterol transport deserves to be addressed. Cholesteryl ester transfer protein cetp also called plasma lipid transfer protein is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. Riikka vikstedt the role of phospholipid transfer protein and cholesteryl ester transfer protein in reverse cholesterol transport academic dissertation. These include but are not limited to lecithincholesterol acyltransferase lcat that catalyzes esterification of free cholesterol in the plasma apo a 1 that is the principal apolipoprotein constituent of hdl cholesterol ester transfer protein cetp that mediates transfer of cholesterol ester from hdl to ldl in exchange for triglyceride . The plasma cholesteryl ester transfer protein cetp modulates hdl levels and composition it mediates the transfer of cholesteryl ester ce from hdl to triglyceride tg rich lipoproteins lp while tg is transferred in the opposite direction to hdl one way ce transfer from hdl to ldl may also occur
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